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| Cat. Number | KU 55933 |
| Chemical Name | KU 55933 |
| CAS Number | [587871-26-9] |
| Mol. Formula | C21H17NO3S2 |
| Mol. Weight | 395.49 |
| Qty 1 |
10mg |
| Synonym | 2-(4-Morpholinyl)-6-(1-thianthrenyl )-4H-pyran-4-one |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro. Acts as a radio- and chemosensitizer for the treatment of cancer. Purity: >98 % |
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