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/ Products Classification 点击展开+Cat. Number | LU AA33810 |
Chemical Name | LU AA33810 |
CAS Number | [304008-29-5] |
Mol. Formula | C19H25N3O2S3 |
Mol. Weight | 423.62 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[[trans-4-[(4,5-Dihydro[1]benzoth iepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl] methanesulfonamide |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at RT |
References | Potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro). Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478 nM respectively). Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity. Purity: >98 % |
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