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Cat. Number
LU AA33810
Chemical Name
LU AA33810
CAS Number
[304008-29-5]
Mol. Formula
C19H25N3O2S3
Mol. Weight
423.62
Qty 1
10mg
Qty 2
50mg
Synonym
N-[[trans-4-[(4,5-Dihydro[1]benzoth iepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl] methanesulfonamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro). Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478 nM respectively). Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.
Purity: >98 %
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