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Cat. Number
Lovastatin
Chemical Name
Lovastatin
CAS Number
[75330-75-5]
Mol. Formula
C24H36O5
Mol. Weight
404.54
Qty 1
10mg
Qty 2
50mg
Synonym
(2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a -Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4 -hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl -2-methyl butanoate
Solubility
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at RT
References
Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro.
Purity: >99 %
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