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/ Products Classification 点击展开+Cat. Number | Lovastatin |
Chemical Name | Lovastatin |
CAS Number | [75330-75-5] |
Mol. Formula | C24H36O5 |
Mol. Weight | 404.54 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a -Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4 -hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl -2-methyl butanoate |
Solubility | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
Storage condition | Store at RT |
References | Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Purity: >99 % |