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| Cat. Number | Loperamide hydrochloride |
| Chemical Name | Loperamide hydrochloride |
| CAS Number | [34552-83-5] |
| Mol. Formula | C29H33ClN2O2.HCl |
| Mol. Weight | 513.51 |
| Qty 1 |
1g |
| Synonym | 4-(4-Chlorophenyl)-4-hydroxy-N,N-di methyl-α,α-diphenyl-1-piperidinebutanamide hydrochloride |
| Solubility | Soluble to 50 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Store at RT |
| References | High affinity μ-opioid receptor agonist with peripheral selectivity (Ki values are 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca2+ channels and at higher concentrations it reduces Ca2+ flux through NMDA receptor operated channels. Purity: >99 % |
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