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Cat. Number
Linopirdine dihydrochloride
Chemical Name
Linopirdine dihydrochloride
CAS Number
[105431-72-9]
Mol. Formula
C26H21N3O.2HCl
Mol. Weight
464.39
Qty 1
10mg
Qty 2
50mg
Synonym
1,3-Dihydro-1-phenyl-3,3-bis(4-pyri dinylmethyl)-2H-indol-2-one dihydrochloride
Solubility
Soluble to 100 mM in water
Storage condition
Desiccate at RT
References
Blocker of KCNQ voltage-gated potassium channels; blocks KCNQ2+3/M-currents (IC50 = 4 - 7 μM) and KCNQ1 homomeric channels (IC50 = 8.9 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo.
Purity: >99 %
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