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Cat. Number
LG 101506
Chemical Name
LG 101506
CAS Number
[331248-11-4]
Mol. Formula
C25H34F2O3
Mol. Weight
420.53
Qty 1
10mg
Qty 2
50mg
Synonym
(2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy )-3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-2,4,6 -octatrienoic acid
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at +4°C
References
Selective RXR modulator (Ki values are 3, 9 and 11 for RXRα, RXRβ and RXRγ respectively). Displays poor binding affinity for RAR isoforms (Ki values are 2746, 3516 and >10,000 nM for RARα, RARβ and RARγ respectively). Binding to RXR results in selective activation of RXR:PPARγ, RXR:PPARα and RXR:PPARδ heterodimers.
Purity: >98 %
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