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| Cat. Number | L-838,417 |
| Chemical Name | L-838,417 |
| CAS Number | [286456-42-6] |
| Mol. Formula | C19H19F2N7O |
| Mol. Weight | 399.4 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-(2,5-Difluorophenyl)-7-(1,1-dimet hylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)metho xy]-1,2,4-triazolo[4,3-b]pyridazine |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Subtype-selective GABAA receptor partial agonist. Selectively binds to α1, α2, α3 and α5 subunits (Ki values are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α1 (α1-sparing). Exhibits non-sedative anxiolytic, antinociceptive and anti-inflammatory activity in vivo. Purity: >98 % |
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