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/ Products Classification 点击展开+Cat. Number | MMPIP hydrochloride |
Chemical Name | MMPIP hydrochloride |
CAS Number | [479077-02-6] |
Mol. Formula | C19H15N3O3.HCl |
Mol. Weight | 369.8 |
Qty 1 |
1mg |
Qty 2 | 50mg |
Synonym | 6-(4-Methoxyphenyl)-5-methyl-3-(4-p yridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride |
Solubility | Soluble to 10 mM in DMSO |
Storage condition | Desiccate at RT |
References | Potent allosteric mGlu7-selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC50 = 15 nM), indicating inverse agonist activity. Purity: >98 % |