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| Cat. Number | MK 571 |
| Chemical Name | MK 571 |
| CAS Number | [115104-28-4] |
| Mol. Formula | C26H27ClN2O3S2 |
| Mol. Weight | 515.09 |
| Qty 1 |
10mg |
| Synonym | 3-[[[3-[(1E)-2-(7-Chloro-2-quinolin yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl] thio]methyl]thio]propanoic acid |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent CysLT1 (LTD4) leukotriene receptor inverse agonist (EC50 = 1.3 nM). Antagonizes LTD4-induced contractions of guinea pig trachea and ileum (pA2 values are 9.4 and 10.5 respectively). Also inhibitor of multidrug resistance protein-1 (MRP1) mediated transport; in vitro augments the effects of cytotoxic agents on malignant cells. |
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