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Cat. Number
Mithramycin A
Chemical Name
Mithramycin A
CAS Number
[18378-89-7]
Mol. Formula
C52H76O24
Mol. Weight
1085.16
Qty 1
1mg
Synonym
(1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-d ideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)- β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3- C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6- dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-did eoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahy dro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1 -O-methyl-D-threo-2-pentulose
Solubility
Soluble to 100 mM in DMSO
Storage condition
Desiccate at -20°C
References
Anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Inhibits c-myc expression and induces myeloid differentiation of HL-60 promyelocytic leukemia cells.
Purity: >95 %
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