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Cat. Number
MIRA-1
Chemical Name
MIRA-1
CAS Number
[72835-26-8]
Mol. Formula
C8H9NO4
Mol. Weight
183.16
Qty 1
10mg
Qty 2
50mg
Synonym
1-[(1-Oxopropoxy)methyl]-1H-pyrrole -2,5-dione
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro (IC50 = 10μM).
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