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/ Products Classification 点击展开+Cat. Number | MIRA-1 |
Chemical Name | MIRA-1 |
CAS Number | [72835-26-8] |
Mol. Formula | C8H9NO4 |
Mol. Weight | 183.16 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 1-[(1-Oxopropoxy)methyl]-1H-pyrrole -2,5-dione |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at +4°C |
References | Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro (IC50 = 10μM). |