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Cat. Number
MG 132
Chemical Name
MG 132
CAS Number
[133407-82-6]
Mol. Formula
C26H41N3O5
Mol. Weight
475.63
Qty 1
5mg
Synonym
N-[(Phenylmethoxy)carbonyl]-L-leucy l-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Solubility
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at -20°C
References
Potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM). Inhibits TNF-α-induced NF-κB activation and IκBα degradation. Induces neurite outgrowth in PC12 cells and has anticancer properties in vitro.
Purity: >95 %
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