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/ Products Classification 点击展开+Cat. Number | BIO |
Chemical Name | BIO |
CAS Number | [667463-62-9] |
Mol. Formula | C16H10BrN3O6 |
Mol. Weight | 356.17 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (2'Z,3'E)-6-Bromoindirubin-3'-oxime |
Solubility | Soluble to 10 mM in DMSO and to 10 mM in ethanol |
Storage condition | Store at +4°C |
References | Potent and selective, ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 values are 5, 83, 300, 320 and > 10 000 nM at GSK-3, CDK5/p25, CDK2/cyclin A, CDK1/cyclin B and other common kinases respectively). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro. Purity: >98 % |
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