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Cat. Number
BIO
Chemical Name
BIO
CAS Number
[667463-62-9]
Mol. Formula
C16H10BrN3O6
Mol. Weight
356.17
Qty 1
10mg
Qty 2
50mg
Synonym
(2'Z,3'E)-6-Bromoindirubin-3'-oxime
Solubility
Soluble to 10 mM in DMSO and to 10 mM in ethanol
Storage condition
Store at +4°C
References
Potent and selective, ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 values are 5, 83, 300, 320 and > 10 000 nM at GSK-3, CDK5/p25, CDK2/cyclin A, CDK1/cyclin B and other common kinases respectively). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro.
Purity: >98 %
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