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/ Products Classification 点击展开+Cat. Number | Mdivi 1 |
Chemical Name | Mdivi 1 |
CAS Number | [338967-87-6] |
Mol. Formula | C25H10Cl2N2O2S |
Mol. Weight | 353.22 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 3-(2,4-Dichloro-5-methoxyphenyl)-2, 3-dihydro-2-thioxo-4(1H)-quinazolinone |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at -20°C |
References | Selective inhibitor of Dnm1 GTPase (IC50 = 1 - 10 μM); attenuates Dnm1- and Drp1-mediated mitochondrial division. Inhibits mitochondrial outer membrane permeabilization (MOMP) and attenuates apoptosis. |