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Cat. Number
(±)-McN 5652
Chemical Name
(±)-McN 5652
CAS Number
[96795-89-0]
Mol. Formula
C19H21NS
Mol. Weight
295.44
Qty 1
10mg
Qty 2
50mg
Synonym
(6R,10bS)-rel-1,2,3,5,6,10b-Hexahyd ro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquino line
Solubility
Soluble to 50 mM in 1eq. HCl and to 75 mM in DMSO
Storage condition
Store at -20°C
References
Potent, high affinity serotonin re-uptake inhibitor; selective in vivo. Displays moderate selectivity over noradrenalin and dopamine re-uptake in vitro (Ki values are 0.68, 2.9 and 36.8 nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Potently potentiates 5-HT-induced effects in vivo following oral administration. Biological activity resides predominantly in the (+)-enantiomer.
Purity: >98 %
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