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| Cat. Number | Nogo-66 (1-40) |
| Chemical Name | Nogo-66 (1-40) |
| CAS Number | [475221-20-6] |
| Mol. Formula | C206H324N56O65 |
| Mol. Weight | 4625.16 |
| Qty 1 |
1mg |
| Storage condition | Desiccate at -20°C |
| References | Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo. |
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