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| Cat. Number | NNC 05-2090 hydrochloride |
| Chemical Name | NNC 05-2090 hydrochloride |
| CAS Number | [184845-43-0] |
| Mol. Formula | C27H30N2O2.HCl |
| Mol. Weight | 451.01 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-[3-(9H-Carbazol-9-yl)propyl]-4-(2 -methoxyphenyl)-4-piperidinol hydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 13 mM in ethanol |
| Storage condition | Desiccate at RT |
| References | GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α1- and D2-receptors (IC50 values are 266 and 1632 nM respectively). Purity: >98 % |
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