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| Cat. Number | NKH 477 |
| Chemical Name | NKH 477 |
| CAS Number | [138605-00-2] |
| Mol. Formula | C27H43NO8.HCl |
| Mol. Weight | 546.1 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10a R,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b- dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphth o[2,1-b]pyran-6-yl ester β-alanine hydrochloride |
| Solubility | Soluble to 40 mM in water |
| Storage condition | Desiccate at +4°C |
| References | Water-soluble analog of forskolin (Cat. No. 1099) that is a potent activator of adenylyl cyclase; shows some selectivity for cardiac (type V) adenylyl cyclase. Stimulates bronchodilation (EC50 = 32.6 nM) and is an orally active potent positive chronotrope and hypotensive agent in vivo. Also available as part of the PKA Tocriset™. Purity: >98 % |
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