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| Cat. Number | NH 125 |
| Chemical Name | NH 125 |
| CAS Number | [278603-08-0] |
| Mol. Formula | C27H45IN2 |
| Mol. Weight | 524.56 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-Hexadecyl-2-methyl-3-(phenylmethy l)-1H-imidazolium iodide |
| Solubility | Soluble to 100 mM in DMSO and to 75 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Histidine protein kinase and eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Exhibits anticancer activity in a variety of malignant cell lines (IC50 values are 0.7 - 4.8 μM) and blocks G1/S cell cycle progression. Also is an effective antibacterial agent in vitro (IC50 = 6.6 μM) and in vivo. |
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