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Cat. Number
Oncrasin 1
Chemical Name
Oncrasin 1
CAS Number
[75629-57-1]
Mol. Formula
C16H12CINO
Mol. Weight
269.73
Qty 1
10mg
Qty 2
50mg
Synonym
1-[(4-Chlorophenyl)methyl]-1H-indol e-3-carboxaldehyde
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at +4°C
References
Proapoptotic agent that induces abnormal nuclear aggregation of PKCι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo.
Purity: >98 %
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