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/ Products Classification 点击展开+Cat. Number | Omeprazole |
Chemical Name | Omeprazole |
CAS Number | [73590-58-6] |
Mol. Formula | C17H19N3O3S |
Mol. Weight | 345.42 |
Qty 1 |
50mg |
Synonym | 5-Methoxy-2-[[(4-methoxy-3,5-dimeth yl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole |
Solubility | Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | H+,K+-ATPase inhibitor (IC50 = 5.8 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.16 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro. Also inhibits CYP2C19, CYP2C9 and CYP3A (Ki values are 3.1, 40.1 and 84.4 μM respectively) and blocks swelling-dependent chloride channels (ICIswell). Purity: >99 % |
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