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Cat. Number
Omeprazole
Chemical Name
Omeprazole
CAS Number
[73590-58-6]
Mol. Formula
C17H19N3O3S
Mol. Weight
345.42
Qty 1
50mg
Synonym
5-Methoxy-2-[[(4-methoxy-3,5-dimeth yl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
Solubility
Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
H+,K+-ATPase inhibitor (IC50 = 5.8 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.16 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro. Also inhibits CYP2C19, CYP2C9 and CYP3A (Ki values are 3.1, 40.1 and 84.4 μM respectively) and blocks swelling-dependent chloride channels (ICIswell).
Purity: >99 %
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