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/ Products Classification 点击展开+Cat. Number | Purvalanol B |
Chemical Name | Purvalanol B |
CAS Number | [212844-54-7] |
Mol. Formula | C20H25ClN6O3 |
Mol. Weight | 432.91 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (2R)-2-[[6-[(3-Chloro-4-carboxyphen yl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3 -methyl-1-butanol |
Solubility | Soluble to 100 mM in 1eq. NaOH |
Storage condition | Store at +4°C |
References | Cyclin-dependent kinase inhibitor. IC50 values are 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Selective over a range of other protein kinases (IC50 > 10,000 nM). Shown to have antiproliferative properties, mediated by p42/p44 MAPK. Purity: >99 % |
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