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Cat. Number
Purvalanol A
Chemical Name
Purvalanol A
CAS Number
[212844-53-6]
Mol. Formula
C19H25ClN6O
Mol. Weight
388.9
Qty 1
10mg
Qty 2
50mg
Synonym
(2R)-2-[[6-[(3-Chlorophenyl)amino]- 9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1- butanol
Solubility
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Cyclin-dependent kinase inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Reversibly arrests synchronised cells in G1 and G2, and inhibits cell proliferation and cell death.
Purity: >98 %
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