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/ Products Classification 点击展开+Cat. Number | PSB 11 hydrochloride |
Chemical Name | PSB 11 hydrochloride |
CAS Number | [444717-56-0] |
Mol. Formula | C16H17N5O.HCl |
Mol. Weight | 331.8 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (8R)-8-Ethyl-1,4,7,8-tetrahydro-4-5 H-imidazo[2,1-i]purin-5-one hydrochloride |
Solubility | Soluble to 20 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent and selective antagonist for the human adenosine A3 receptor, with low affinity for the rat A3 receptor (Ki values are 2.3 and > 10000 nM respectively). Displays > 1000-fold selectivity over human A1 and A2A receptors (Ki values are 4.1 and 3.3 μM respectively) and > 180-fold selectivity over rat A1, rat A2A and mouse A2B receptors. Acts as an inverse agonist in the [35S]GTPγS binding assay in hA3-CHO cells (IC50 = 36 nM). Purity: >98 % |
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