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Cat. Number
PSB 11 hydrochloride
Chemical Name
PSB 11 hydrochloride
CAS Number
[444717-56-0]
Mol. Formula
C16H17N5O.HCl
Mol. Weight
331.8
Qty 1
10mg
Qty 2
50mg
Synonym
(8R)-8-Ethyl-1,4,7,8-tetrahydro-4-5 H-imidazo[2,1-i]purin-5-one hydrochloride
Solubility
Soluble to 20 mM in DMSO
Storage condition
Store at +4°C
References
Potent and selective antagonist for the human adenosine A3 receptor, with low affinity for the rat A3 receptor (Ki values are 2.3 and > 10000 nM respectively). Displays > 1000-fold selectivity over human A1 and A2A receptors (Ki values are 4.1 and 3.3 μM respectively) and > 180-fold selectivity over rat A1, rat A2A and mouse A2B receptors. Acts as an inverse agonist in the [35S]GTPγS binding assay in hA3-CHO cells (IC50 = 36 nM).
Purity: >98 %
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