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| Cat. Number | PSB 10 hydrochloride |
| Chemical Name | PSB 10 hydrochloride |
| CAS Number | [591771-91-4] |
| Mol. Formula | C16H14Cl3N5O.HCl |
| Mol. Weight | 435.14 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 8-Ethyl-1,4,7,8-tetrahydro-4-methyl -2-(2,3,5-trichlorophenyl)-5H-imidazo[2,1-i]purin- 5-one monohydrochloride |
| Solubility | Soluble to 25 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Desiccate at +4°C |
| References | Potent and highly selective antagonist for the human adenosine A3 receptor, with low affinity for the rat A3 receptor (Ki values are 0.44 and > 17000 nM respectively). Displays > 3800-fold selectivity over human A1, A2A and A2B receptors (Ki values are 4.1, 3.3 and 30 μM respectively) and > 1800-fold selectivity over rat A1 and A2A receptors. Acts as an inverse agonist in the [35S]GTPγS binding assay in hA3-CHO cells (IC50 = 4 nM). Produces thermal hyperalgesia in mice in vivo. Purity: >98 % |
下一个：PSB 11 hydrochloride上一个：PSB 0788 |
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