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Cat. Number
PP 2
Chemical Name
PP 2
CAS Number
[172889-27-9]
Mol. Formula
C15H16ClN5
Mol. Weight
301.78
Qty 1
10mg
Synonym
3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3 ,4-d]pyrimidin-4-amine
Solubility
Soluble to 25 mM in DMSO and to 10 mM in ethanol
Storage condition
Desiccate at +4°C
References
Selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM). Negative control PP 3 (Cat. No. 2794) also available.
Purity: >99 %
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