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/ Products Classification 点击展开+Cat. Number | PHA 568487 |
Chemical Name | PHA 568487 |
CAS Number | [527680-56-4] |
Mol. Formula | C16H20N2O3.C4H4O4 |
Mol. Weight | 404.41 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl- 2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5% for α4β2 and hERG respectively). Orally active and brain penetrant. Purity: >99 % |