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Cat. Number
PHA 568487
Chemical Name
PHA 568487
CAS Number
[527680-56-4]
Mol. Formula
C16H20N2O3.C4H4O4
Mol. Weight
404.41
Qty 1
10mg
Qty 2
50mg
Synonym
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl- 2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5% for α4β2 and hERG respectively). Orally active and brain penetrant.
Purity: >99 %
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