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Cat. Number
PG 01037 dihydrochloride
Chemical Name
PG 01037 dihydrochloride
CAS Number
[790658-27-4]
Mol. Formula
C26H26Cl2N4O.2HCl
Mol. Weight
554.34
Qty 1
10mg
Qty 2
50mg
Synonym
N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1 -piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamid e dihydrochloride
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
Dopamine D3 receptor antagonist; 133-fold selective for D3 over D2 receptors in vitro (Ki values are 0.70, 93.3 and 375 nM for D3, D2 and D4 receptors respectively). Attenuates abnormal involuntary movements associated with L-DOPA (Cat. No. 3788) in rat models of Parkinson's disease. Inhibits the effects of methamphetamine; attenuates drug-induced behaviors in vivo.
Purity: >99 %
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