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| Cat. Number | PD 176252 |
| Chemical Name | PD 176252 |
| CAS Number | [204067-01-6] |
| Mol. Formula | C32H36N6O5 |
| Mol. Weight | 584.67 |
| Qty 1 |
10mg |
| Synonym | (S)-N-[[1-(5-Methoxy-2-pyridinyl)cy clohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino ]carbonyl]amino-1H-indole-3-propanamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Non-peptide gastrin-releasing peptide receptor (GRP-R, BB2) and neuromedin B receptor (NMB-R, BB1) antagonist (Ki values are 0.17 and 1.0 nM for BB1 and BB2 respectively). Inhibits proliferation of rat C6 glioma cells (IC50 = 2 μM) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC50 = 5 μM). Purity: >98 % |
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