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Cat. Number
PD 168368
Chemical Name
PD 168368
CAS Number
[204066-82-0]
Mol. Formula
C31H34N6O4
Mol. Weight
554.65
Qty 1
1mg
Qty 2
10mg
Synonym
(S)-α-Methyl-α-[[[(4-nitrophenyl)amin o]carbonyl]amino]-N-[[1-(2-pyridinyl)cyclohexyl]me thyl]-1H-indole-3-propanamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent neuromedin B receptor antagonist (NMB-R, BB1) (IC50 = 40 nM) that displays ~ 40-fold selectivity over the gastrin-releasing peptide receptor (GRP-R, BB2) and > 300-fold selectivity over BRS-R (bb3). Antagonizes neuromedin B-stimulated calcium release and inhibits proliferation of rat glioma cells (IC50 = 2 μM).
Purity: >96 %
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