服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | PD 168368 |
Chemical Name | PD 168368 |
CAS Number | [204066-82-0] |
Mol. Formula | C31H34N6O4 |
Mol. Weight | 554.65 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Synonym | (S)-α-Methyl-α-[[[(4-nitrophenyl)amin o]carbonyl]amino]-N-[[1-(2-pyridinyl)cyclohexyl]me thyl]-1H-indole-3-propanamide |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent neuromedin B receptor antagonist (NMB-R, BB1) (IC50 = 40 nM) that displays ~ 40-fold selectivity over the gastrin-releasing peptide receptor (GRP-R, BB2) and > 300-fold selectivity over BRS-R (bb3). Antagonizes neuromedin B-stimulated calcium release and inhibits proliferation of rat glioma cells (IC50 = 2 μM). Purity: >96 % |