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/ Products Classification 点击展开+Cat. Number | PD 146176 |
Chemical Name | PD 146176 |
CAS Number | [4079-26-9] |
Mol. Formula | C15H11NS |
Mol. Weight | 237.32 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 6,11-Dihydro[1]benzothiopyrano[4,3- b]indole |
Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
Storage condition | Store at +4°C |
References | Specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM) that has no demonstrable effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC50 = 0.54 μM for 15-LOX in rabbit reticulocytes). Lacks non-specific antioxidant properties and prevents atherogenesis via regulation of monocyte-macrophage enrichment in vivo. Purity: >98 % |
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