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Cat. Number
PB 28 dihydrochloride
Chemical Name
PB 28 dihydrochloride
CAS Number
[172906-90-0]
Mol. Formula
C24H38N2O.2HCl
Mol. Weight
443.5
Qty 1
10mg
Qty 2
50mg
Synonym
1-Cyclohexyl-4-[3-(1,2,3,4-tetrahyd ro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride
Solubility
Soluble to 20 mM in water
Storage condition
Desiccate at +4°C
References
High affinity σ2 receptor agonist (Ki values are 0.8 and 15.2 nM for σ2 and σ1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC50 values are 2.62 and 3.96 μM respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.
Purity: >99 %
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