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Cat. Number
Ro 19-4603
Chemical Name
Ro 19-4603
CAS Number
[99632-94-7]
Mol. Formula
C15H17N3O3S
Mol. Weight
319.38
Qty 1
10mg
Qty 2
50mg
Synonym
5,6-Dihydro-5-methyl-6-oxo-4H-imida zo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid 1,1-dimethylethyl ester
Solubility
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at RT
References
Benzodiazepine inverse agonist. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors (Ki values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Antagonizes effects of ethanol on locomotor behavior and suppresses ethanol intake in alcohol-preferring rats.
Purity: >99 %
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