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Cat. Number
Ro 15-4513
Chemical Name
Ro 15-4513
CAS Number
[91917-65-6]
Mol. Formula
C15H14N6O3
Mol. Weight
326.31
Qty 1
10mg
Qty 2
50mg
Synonym
8-Azido-5,6-dihydro-5-methyl-6-oxo- 4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
Solubility
Soluble to 5 mM in ethanol and to 10 mM in DMSO
Storage condition
Desiccate at +4°C
References
High affinity benzodiazepine ligand. Ki values are 3.1 and 5.3 nM for diazepam-insensitive (DI) and diazepam-sensitive (DS) benzodiazepine receptors respectively. Acts as partial inverse agonist at recombinant DS α1-, α2-, α3- and α5-GABAA receptors. Displays partial agonism at DI α4- and α6-GABAA receptors. Antagonizes several behavioral and neurochemical effects of ethanol. Proconvulsant and anxiogenic.
Purity: >98 %
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