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| Cat. Number | TOC1292 |
| Chemical Name | Rapamycin |
| CAS Number | 53123-88-9 |
| Mol. Formula | C51H79NO13 |
| Mol. Weight | 914.18 |
| Qty 1 |
1mg |
| Synonym | (3S,6R,7E,9R,10R,12R,14S,15E,17E,19 E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24, 25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3- [(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl] -1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-he xamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacy clohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Solubility | Soluble to 100 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Desiccate at -20°C |
| References |
Antifungal and immunosuppressant. Specific inhibitor of mTOR (mammalian target of Rapamycin). Complexes with FKBP-12 and binds mTOR inhibiting its activity. Inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase. |
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