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Cat. Number
SYM 2206
Chemical Name
SYM 2206
CAS Number
[173952-44-8]
Mol. Formula
C20H22N4O3
Mol. Weight
366.42
Qty 1
10mg
Qty 2
50mg
Synonym
(±)-4-(4-Aminophenyl)-1,2-dihydro-1- methyl-2-propylcarbamoyl-6,7-methylenedioxyphthala zine
Solubility
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at RT
References
Novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo.
Purity: >99 %
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