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Cat. Number
SU 5402
Chemical Name
SU 5402
CAS Number
[215543-92-3]
Mol. Formula
C17H16N2O3
Mol. Weight
296.32
Qty 1
1mg
Synonym
2-[(1,2-Dihydro-2-oxo-3H-indol-3-yl idene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid
Solubility
Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Storage condition
Store at -20°C
References
Potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively). Inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo.
Purity: >95 %
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