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Cat. Number
SNAP 5089
Chemical Name
SNAP 5089
CAS Number
[157066-76-7]
Mol. Formula
C36H40N4O5.HCl
Mol. Weight
645.19
Qty 1
10mg
Qty 2
50mg
Synonym
5-[[[3-(4,4-Diphenyl-1-piperidinyl) propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4- (4-nitrophenyl)-3-pyridinecarboxylic acid methyl ester hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Subtype-selective α1A-adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (Kivalues are 0.35, 220, 370, 540, 800 and 1200 nM for α1A, α1B, α2C, α1D, α2B and α2A subtypes respectively and 540 nM for L-type Ca2+ channels). Inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues.
Purity: >98 %
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