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/ Products Classification 点击展开+Cat. Number | SN 003 |
Chemical Name | SN 003 |
CAS Number | [197801-88-0] |
Mol. Formula | C19H25N5O2 |
Mol. Weight | 355.43 |
Qty 1 |
10mg |
Synonym | N-(4-Methoxy-2-methylphenyl)-1-[1-( methoxymethyl)propyl]-6-methyl-1H-1,2,3-triazolo[4 ,5-c]pyridin-4-amine |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at +4°C |
References | Reversible corticotropin releasing factor receptor 1 (CRF1) antagonist (Ki values are 3.4 and 7.9 nM at rat and human CRF1 respectively) that displays >1000-fold selectivity over CRF2 receptors. Suppresses CRF-induced ACTH release in vitro (IC50 = 241 nM) and is brain penetrant. Purity: >98 % |
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