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Cat. Number
SN 003
Chemical Name
SN 003
CAS Number
[197801-88-0]
Mol. Formula
C19H25N5O2
Mol. Weight
355.43
Qty 1
10mg
Synonym
N-(4-Methoxy-2-methylphenyl)-1-[1-( methoxymethyl)propyl]-6-methyl-1H-1,2,3-triazolo[4 ,5-c]pyridin-4-amine
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Reversible corticotropin releasing factor receptor 1 (CRF1) antagonist (Ki values are 3.4 and 7.9 nM at rat and human CRF1 respectively) that displays >1000-fold selectivity over CRF2 receptors. Suppresses CRF-induced ACTH release in vitro (IC50 = 241 nM) and is brain penetrant.
Purity: >98 %
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