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/ Products Classification 点击展开+Cat. Number | SL 327 |
Chemical Name | SL 327 |
CAS Number | [305350-87-2] |
Mol. Formula | C16H12F3O3S |
Mol. Weight | 335.35 |
Qty 1 |
1mg |
Qty 2 | 50mg |
Synonym | α-[Amino[(4-aminophenyl)thio]methyle ne]-2-(trifluoromethyl)benzeneacetonitrile |
Solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | Selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain penetrant in vivo, blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration. Purity: >99 % |
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