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/ Products Classification 点击展开+Cat. Number | SB 328437 |
Chemical Name | SB 328437 |
CAS Number | [247580-43-4] |
Mol. Formula | C21H18N2O5 |
Mol. Weight | 378.38 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-(1-Naphthalenylcarbonyl)-4-nitro- L-phenylalanine methyl ester |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent and selective CCR3 antagonist (IC50 = 4 nM). Displays > 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20 nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies. Purity: >99 % |