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Cat. Number
SB 228357
Chemical Name
SB 228357
CAS Number
[181629-93-6]
Mol. Formula
C22H17F4N3O2
Mol. Weight
431.39
Qty 1
10mg
Qty 2
50mg
Synonym
N-[3-Fluoro-5-(3-pyrindyl)phenyl]-2 ,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole -1-carboxamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
5-HT2C/2B receptor antagonist (pKi values are 7.0, 8.1 and 9.1 at 5-HT2A, 2B and 2C receptors respectively). Displays inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT2C receptor function. Orally active in vivo.
Purity: >99 %
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