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Cat. Number
SANT-2
Chemical Name
SANT-2
CAS Number
[329196-48-7]
Mol. Formula
C25H25ClN3O4
Mol. Weight
479.96
Qty 1
10mg
Qty 2
50mg
Synonym
N-[3-(1H-Benzimidazol-2-yl)-4-chlor ophenyl]-3,4,5-triethoxybenzamide
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at RT
References
Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (KD = 12 nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[3H]SAG-1.3 and -[3H]Cyclopamine binding (Ki values are 7.8 nM and 8.4 nM respectively).
Purity: >98 %
下一个:SANT-1上一个:Sanguinarine chloride
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