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/ Products Classification 点击展开+Cat. Number | SANT-2 |
Chemical Name | SANT-2 |
CAS Number | [329196-48-7] |
Mol. Formula | C25H25ClN3O4 |
Mol. Weight | 479.96 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[3-(1H-Benzimidazol-2-yl)-4-chlor ophenyl]-3,4,5-triethoxybenzamide |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at RT |
References | Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (KD = 12 nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[3H]SAG-1.3 and -[3H]Cyclopamine binding (Ki values are 7.8 nM and 8.4 nM respectively). Purity: >98 % |
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