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Cat. Number
S-Trityl-L-cysteine
Chemical Name
S-Trityl-L-cysteine
CAS Number
[2799-07-7]
Mol. Formula
C22H21NO2S
Mol. Weight
363.47
Qty 1
50mg
Synonym
S-(Triphenylmethyl)-L-cysteine
Solubility
Soluble to 50 mM in DMSO
Storage condition
Store at +4°C
References
Potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, a protein required for establishing and maintaining a bipolar spindle. Inhibits basal ATPase activity (IC50 = 1 mM) and microtubule-activated ATPase activity of Eg5 (IC50 = 140 nM). Induces mitotic arrest in HeLa cells with an IC50 of 700 nM. Displays antitumor activity.
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