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Cat. Number
Trequinsin hydrochloride
Chemical Name
Trequinsin hydrochloride
CAS Number
[78416-81-6]
Mol. Formula
C24H27N3O3.HCl
Mol. Weight
441.95
Qty 1
10mg
Synonym
2,3,6,7-Tetrahydro-9,10-dimethoxy-3 -methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimi do[6,1-a]isoquinolin-4-one hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Desiccate at RT
References
Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.
Purity: >97 %
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