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| Cat. Number | Topiramate |
| Chemical Name | Topiramate |
| CAS Number | [97240-79-4] |
| Mol. Formula | C21H21NO8S |
| Mol. Weight | 339.36 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2,3:4,5-Bis-O-(1-methylethylidene)- β-D-fructopyranose sulfamate |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Anticonvulsant. Antagonizes GluR5 kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH. Purity: >99 % |
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