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/ Products Classification 点击展开+Cat. Number | TMCB |
Chemical Name | TMCB |
CAS Number | [905105-89-7] |
Mol. Formula | C11H9Br4N3O2 |
Mol. Weight | 534.82 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-(4,5,6,7-Tetrabromo-2-(dimethylam ino)-1H-benzo[d]imidazol-1-yl)acetic acid |
Solubility | Soluble to 25 mM in DMSO |
Storage condition | Store at RT |
References | Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2 respectively). Purity: >98 % |