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Cat. Number
TMCB
Chemical Name
TMCB
CAS Number
[905105-89-7]
Mol. Formula
C11H9Br4N3O2
Mol. Weight
534.82
Qty 1
10mg
Qty 2
50mg
Synonym
2-(4,5,6,7-Tetrabromo-2-(dimethylam ino)-1H-benzo[d]imidazol-1-yl)acetic acid
Solubility
Soluble to 25 mM in DMSO
Storage condition
Store at RT
References
Dual-kinase inhibitor; inhibits both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). Displays selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki values are 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2 respectively).
Purity: >98 %
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