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Cat. Number
TC-A 2317 hydrochloride
Chemical Name
TC-A 2317 hydrochloride
CAS Number
[1245907-03-2]
Mol. Formula
C19H28N6O.HCl
Mol. Weight
392.93
Qty 1
10mg
Qty 2
50mg
Synonym
2-[(5-Hydroxy-1,5-dimethylhexyl)ami no]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3 -pyridinecarbonitrile hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at +4°C
References
Potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.
Purity: >98 %
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