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Cat. Number
TBB
Chemical Name
TBB
CAS Number
[17374-26-4]
Mol. Formula
C6HBr4N3
Mol. Weight
434.71
Qty 1
10mg
Qty 2
50mg
Synonym
4,5,6,7-Tetrabromobenzotriazole
Solubility
Soluble to 100 mM in DMSO and to 15 mM in ethanol
Storage condition
Store at +4°C
References
A cell-permeable, selective inhibitor of casein kinase-2 (CK2) (IC50 = 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively). Exhibits modest discrimination between CK2 subunits, with Ki values ranging from 80 nM to 210 nM. Acts in an ATP/GTP-competitive manner and displays one to two orders of magnitude selectivity over a panel of 33 protein kinases.
Purity: >99 %
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