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| Cat. Number | Tazarotene |
| Chemical Name | Tazarotene |
| CAS Number | [118292-40-3] |
| Mol. Formula | C21H21NO2S |
| Mol. Weight | 351.46 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1 -benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic acid ethyl ester |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Receptor-selective acetylenic retinoid; binds at retinoid acid receptors (RAR) -β and -γ. Topically used for the treatment of skin disorders, particularly psoriasis and acne. Implicated in the treatment of basal cell carcinomas; induces upregulation of Bax in vivo. Exhibits anti-proliferative and pro-apoptotic activity. Upregulates TIGs (Tazarotene-induced genes), including the cell adhesion molecule TIG1 and the tumor-suppressor TIG3. Purity: >99 % |
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